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University of Pittsburgh    
2022-2023 Graduate & Professional Studies Catalog 
    
 
  May 28, 2024
 
2022-2023 Graduate & Professional Studies Catalog [Archived Catalog]

Pharmaceutical Sciences - Pharmacometrics and Systems Pharmacology Track, MS


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The Pharmacometrics and Systems Pharmacology (PSP) is an interdisciplinary science to study drug actions and rational development of new drugs through network analysis, multitype-multiscale modeling and simulations “mechanism-driven”, as well as data analysis “data-driven”. The PSP track focuses on applying Pharmacometrics and System Pharmacology techniques to facilitate the development of novel drug candidates that are less likely to fail during clinical trials and to provide a better understanding of drug mechanisms of action and therapeutic effects at the systems pharmacology level.

  • You will develop a broad knowledge of pharmacometrics and systems pharmacology to develop drug candidates that are less likely to fail during clinical trials.
  • You will develop strong computational modeling and simulation expertise from drug target fishing, to drug lead identification, to drug profile optimization.
  • You will develop strong computational expertise on pharmacokinetics (PK) and pharmacodynamics (PD) modeling and simulation.
  • You will develop skills on multiscale modeling of biological processes at the molecular, gene, organ and organism levels.
  • Your will have opportunities to study with faculty from a variety of background including computer-aided drug design, computational and systems biology/pharmacology, population PK/PD modeling, computational chemical genomics, computational biophysics, etc.
  • Candidates with programming experience, basic/intermediate knowledge in statistics and/or hands-on modeling experience are highly desired.

This program is associated with the Computational Chemical Genomics Screening Center. More about this program track is here.

MS Core Curriculum


Requirements:


Students must complete a total of 30 credit hours to fulfill the requirements for the MS. Required courses for all MS students are listed below. Students who have had prior course work or extensive experience in a given area may be exempted from the required course at the discretion of the faculty. The remaining credit requirements are completed through elective courses and thesis research. The specific plan of study is developed by the student and their faculty advisor and committee. Courses should be selected to assure an adequate breadth of knowledge as well as depth in the student’s focus area.

MS Comprehensive Exam and Thesis


The thesis for the MS must represent an original research project or a comprehensive and detailed survey of some topic of current interest in the pharmaceutical sciences. It must be defended in an oral examination.

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