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BIOENG 1384 - APPLC OF NMR SPCTRSCPY IN MEDMinimum Credits: 3 Maximum Credits: 3 This course constitutes into two parts. The first part is intended to teach basic understanding of nuclear magnetic resonance (NMR) spectroscopy with numerous examples. Development of two-dimensional, three- dimensional NMR spectroscopy. Focus will be given to design of different NMR experiments for drug discovery, protein structure determination and dynamics of protein molecule. Special emphasis will be given to product operator formalism and different 2d and 3d NMR experiments will be explained with the help of product operator formalism. Classes will focus on NMR data analysis and protein structure calculation. The second part of the course will teach brain imaging using functional imaging (FMRI) and magnetic resonance spectroscopy (MRS) methodology and their application to different neurodegenerative diseases such as Alzheimer and Parkinson disease. Academic Career: UGRD Course Component: Lecture Grade Component: Letter Grade Course Requirements: PROG: Swanson School of Engineering
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