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BIOSC 2075 - MOLECULAR EVOLUTIONMinimum Credits: 3 Maximum Credits: 3 Sequencing technology is continually progressing, and genome sequences from different species and populations continue to become available in increasing numbers. Such data allows questions about molecular evolution to be addressed in new and exciting ways. This course introduces students to the evolutionary analysis of DNA and amino acid sequences. Lectures on theory will be accompanied by practical instruction in the use of contemporary computational methods and software. Topics include: population genetics of selection and mutation, models of sequence evolution, phylogenetic models, analysis of multiple sequence alignments for rates and patterns of divergence, inference of natural selection, and co-evolution between proteins. Emphasis is placed on quantitative modeling and the biological principles underlying observed patterns of molecular evolution. Interested students should have a basic grasp of molecular biology and calculus. Academic Career: Graduate Course Component: Lecture Grade Component: Grad LG/SNC Basis
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